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This detailed collection explores techniques involved in the main strategies of nanopore sensing, such as translocation, analyte trapping, and interactions with external binding sites. Opening with a section on nanopore design and nanopore production, the book continues with parts devoted to various biological nanopores, nanopore engineering, and their uses in single molecule sensing, computational methods to study intrinsic nanopore behavior, characterizing the specific translocation activity of a vesicle particle through a nanopore, as well as the use of the technique droplet interface bilayer (DIB) in nanopore and membrane biophysical studies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Nanopore Technology: Methods and Protocols, with its focus on nanopore technology and biomolecule characterization, will hold the interest of the biophysicists, biochemists, bioengineers, and molecular biologists who are working toward further understanding this key field of research.

Proteins. --- Biophysics. --- Biotechnology. --- Protein Biochemistry. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Biological physics --- Biology --- Medical sciences --- Physics --- Chemical engineering --- Genetic engineering

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Biomembranes --- General biophysics --- membranen (biologie) --- biofysica --- Animal mechanics. --- Biophysics. --- Biological physics --- Biology --- Medical sciences --- Physics --- Animal movements (Physiology) --- Body mechanics, Animal --- Movements of animals (Physiology) --- Biomechanics --- Physiology

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This book talks about photoplethysmography (PPG) techniques based on computer-aided data processing. In particular, it presents the results of a co-operative Indo-German project on the topic between Indian Institute of Technology at Chennai and RWTH Aachen University. Measuring system design, experimental details and some preliminary results obtained so far within the framework of this project are presented here. From the investigations carried out so far using the PPG sensors in conjunction with breathing sensors, it has been possible to monitor the 0.125 to 0.15 Hz rhythms in the arterial volumetric changes and to study the influence of breathing on them. These rhythms, which according to medical experts have relevance to psychosomatic conditions e.g. stress or relaxation, can also be addressed to by ancient Indian practices like yoga and meditation. This book presents the results of studying the effects of Indian relaxation techniques like pranayama, meditation, etc. in comparison to western relaxation techniques like autogenic training. So far it has been established that the Indian techniques of relaxation like yoga and meditation are very effective in generating low frequency rhythms in the skin perfusion as monitored by optical sensors. According to medical experts, these low frequency rhythms have a very important bearing on the human physiology and have potential therapeutic implications. This book is meant to provide an overview of the current state-of-knowledge and encourage the next generation of scientists/engineers to carry this work forward, especially on the novel PPG application fields that are of growing importance like pain and stress assessment, detection of peripheral venous saturation and local arterio-venous oxygen consumption as well as contactless space resolved skin perfusion studies with modern camera based PPG technology.

Biophysics. --- Biological physics. --- Biomedical engineering. --- Radiology. --- Biological and Medical Physics, Biophysics. --- Biomedical Engineering and Bioengineering. --- Imaging / Radiology. --- Radiological physics --- Physics --- Radiation --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biological physics --- Biology --- Medical sciences --- Plethysmography. --- Respiration --- Perfusion (Physiology) --- Measurement. --- Pulmonary function tests --- Respirometer --- Blood --- Blood flow --- Body fluids --- Physiology --- Circulation --- Measurement

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This book, based on a selection of invited presentations from a topical workshop, focusses on time-variable oscillations and their interactions. The problem is challenging, because the origin of the time variability is usually unknown. In mathematical terms, the oscillations are non-autonomous, reflecting the physics of open systems where the function of each oscillator is affected by its environment. Time-frequency analysis being essential, recent advances in this area, including wavelet phase coherence analysis and nonlinear mode decomposition, are discussed. Some applications to biology and physiology are described. Although the most important manifestation of time-variable oscillations is arguably in biology, they also crop up in, e.g. astrophysics, or for electrons on superfluid helium. The book brings together the research of the best international experts in seemingly very different disciplinary areas. .

Biophysics. --- Biological physics. --- Systems biology. --- Statistical physics. --- Biomedical engineering. --- Biological and Medical Physics, Biophysics. --- Systems Biology. --- Applications of Nonlinear Dynamics and Chaos Theory. --- Statistical Physics and Dynamical Systems. --- Biomedical Engineering and Bioengineering. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Physics --- Mathematical statistics --- Computational biology --- Bioinformatics --- Biological systems --- Molecular biology --- Biological physics --- Biology --- Medical sciences --- Statistical methods

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Meningiomas are the most frequently reported neuro-oncologic condition, accounting for 12% to 30% of all primary intracranial tumors. The first case of intracranial meningioma treated with stereotactic radiosurgery was reported by Backlund E-O in 1971. Since then, more than 200,000 meningiomas have been treated with stereotactic radiosurgery worldwide to date. The large number of patients treated using this method is due to the fact that meningiomas are frequently located in critical areas and microsurgery is often associated with severe and permanent neurological complications. This book discusses the advantages, risks and limits of stereotactic radiosurgery relating to all regions of interest for a neuroradiosurgical approach for the treatment of central nervous system meningiomas. Firstly, it presents an introduction focusing on the “state of the art”. It then discusses the physics, imaging, neurological and neuro-oncological issues in multidisciplinary management. Lastly, it features a summary of results, including the most recent published papers regarding all the locations involved in the stereotactic radiosurgery treatment as well as new approaches to meningiomas, with particular reference to the hypofrationated treatments. Intended for anyone involved in the neuroradiosurgical treatment of brain diseases, the book provides an up-to-date overview of the latest stereotactic radiosurgery treatment of central nervous system meningiomas.

Neurosurgery. --- Radiotherapy. --- Biophysics. --- Biological physics. --- Neuroradiology. --- Neurology . --- Neurosciences. --- Biological and Medical Physics, Biophysics. --- Neurology. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Medicine --- Neuropsychiatry --- Neuroradiography --- Neuroradiology --- Biological physics --- Biology --- Physics --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Nerves --- Neurosurgery --- Diseases --- Radiological services --- Surgery --- Meningioma --- Surgery. --- Brain --- Tumors --- Radiocirurgia --- Tumors cerebrals --- Neurocirurgia --- Radioteràpia